Immune regulation by glucocorticoids

@article{Cain2017ImmuneRB,
  title={Immune regulation by glucocorticoids},
  author={D. Cain and J. Cidlowski},
  journal={Nature Reviews Immunology},
  year={2017},
  volume={17},
  pages={233-247}
}
Endogenous glucocorticoids are crucial to various physiological processes, including metabolism, development and inflammation. Since 1948, synthetic glucocorticoids have been used to treat various immune-related disorders. The mechanisms that underlie the immunosuppressive properties of these hormones have been intensely scrutinized, and it is widely appreciated that glucocorticoids have pleiotropic effects on the immune system. However, a clear picture of the cellular and molecular basis of… Expand

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