Immune privilege in hair growth.

  title={Immune privilege in hair growth.},
  author={Gillian E Westgate and Richard Craggs and William Thomas Gibson},
  journal={The Journal of investigative dermatology},
  volume={97 3},
Immunostaining techniques were used to investigate the relationship between immune cells, proteoglycan, and class I MHC distribution in skin during the hair cycle in rats. The growth stage, anagen, was characterized by absence of class I MHC staining on most cells of the lower follicle and presence of chondroitin proteoglycan in the follicle sheath and dermal papilla. Immune cells were few in number and not associated with follicles. Dramatic changes were observed during regression in catagen… CONTINUE READING