Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence

@inproceedings{McNeilly2014ImmuneMB,
  title={Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence
},
  author={Tom N McNeilly and Alasdair J. Nisbet},
  booktitle={Parasite},
  year={2014}
}
Parasitic helminths reside in immunologically-exposed extracellular locations within their hosts, yet they are capable of surviving for extended periods. To enable this survival, these parasites have developed complex and multifaceted mechanisms to subvert or suppress host immunity. This review summarises current knowledge of immune modulation by helminth parasites of ruminants and the parasite-derived molecules involved in driving this modulation. Such immunomodulatory molecules have… CONTINUE READING