Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin.


Thrombocytopenia developing in the course of chemotherapy for malignant disease is usually attributed to drug-induced marrow suppression and/or marrow replacement by tumor. We describe two patients who developed severe thrombocytopenia and hemorrhagic symptoms while being treated with oxaliplatin, 5-fluorouracil, and leukovorin for metastatic colon cancer… (More)


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@article{Curtis2006ImmunemediatedTR, title={Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin.}, author={Brian Curtis and James Kaliszewski and Marisa Marques and Mehrdad Saif and Lisle Nabelle and Jules H. Blank and Janice G. McFarland and Richard H. Aster}, journal={American journal of hematology}, year={2006}, volume={81 3}, pages={193-8} }