Immune-mediated drug-induced liver disease.

@article{Liu2002ImmunemediatedDL,
  title={Immune-mediated drug-induced liver disease.},
  author={Zhang-Xu Liu and Neil Kaplowitz},
  journal={Clinics in liver disease},
  year={2002},
  volume={6 3},
  pages={755-74}
}
Drug-induced immune-mediated hepatic injury is an adverse immune response against the liver that results in a disease with hepatitic, cholestatic, or mixed clinical features. Drugs such as halothane, tienilic acid, dihydralazine, and anticonvulsants trigger a hepatitic reaction, and drugs such as chlorpromazine, erythromycins, amoxicillin-calvulanic acid, sulfonamides and sulindac trigger a cholestatic or mixed reaction. Unstable metabolites derived from the metabolism of the drug may bind to… CONTINUE READING
52 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

Similar Papers

Loading similar papers…