Immune mechanisms in inflammatory and degenerative eye disease.

  title={Immune mechanisms in inflammatory and degenerative eye disease.},
  author={Victor L. Perez and Rachel R Caspi},
  journal={Trends in immunology},
  volume={36 6},
It has recently been recognized that pathology of age-associated degenerative eye diseases such as adult macular degeneration (AMD), glaucoma and diabetic retinopathy, have strong immunological underpinnings. Attempts have been made to extrapolate to age-related degenerative disease insights from inflammatory processes associated with non-infectious uveitis, but these have not yet been sufficiently informative. Here we review recent findings on the immune processes underlying uveitis and those… CONTINUE READING