Immune intervention effects on the induction of experimental autoimmune thyroiditis

@article{Chen2002ImmuneIE,
  title={Immune intervention effects on the induction of experimental autoimmune thyroiditis},
  author={Weihong Chen and Hanhua Lin and Muti Wang},
  journal={Journal of Huazhong University of Science and Technology [Medical Sciences]},
  year={2002},
  volume={22},
  pages={343-345}
}
To explore immune intervention effects of the combined use of cycloporin A (CsA) and 1, 25-dihydroxyvitamin D3[1,25(OH)2D3] at low doses on experimental autoimmune thyroiditis (EAT), porcine thyroglobulin (pTG) was injected into a CBA mouse at the dose of 100µg on day 0 and day 14 to establish the model of EAT. The immune prevention group from day 0 to day 28, and treatment group from day 10 to day 38 were daily administered CsA (10 mg/kg) intragastrically and/or 1,25(OH)2D3(0.2µg/kg) ip. After… CONTINUE READING