Immune infiltrates in the breast cancer microenvironment: detection, characterization and clinical implication.

@article{Burugu2017ImmuneII,
  title={Immune infiltrates in the breast cancer microenvironment: detection, characterization and clinical implication.},
  author={Samantha Burugu and Karama Asleh-Aburaya and Torsten O. Nielsen},
  journal={Breast cancer},
  year={2017},
  volume={24 1},
  pages={3-15}
}
Although unlike melanoma, breast cancer is not generally viewed as a highly immunogenic cancer, recent studies have described a rich tumor immune microenvironment in a subset of breast cancers. These immune infiltrates, comprised cells from the innate and adaptive immune response, can be detected and characterized in biopsy specimens and have prognostic value. Tumor-infiltrating lymphocytes (TILs) represent the majority of mononuclear immune infiltrates in the breast tumor microenvironment and… CONTINUE READING
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