Immune hemolytic anemia associated with drug therapy.

  title={Immune hemolytic anemia associated with drug therapy.},
  author={George Garratty},
  journal={Blood reviews},
  volume={24 4-5},
Drug-induced immune hemolytic anemia (DIIHA) is rare; it can be mild or associated with acute severe hemolytic anemia (HA) and death. About 125 drugs have been implicated as the cause. The HA can be caused by drug-independent antibodies that are indistinguishable, in vitro and in vivo, from autoantibodies causing idiopathic warm type autoimmune hemolytic anemia (AIHA). More commonly, the antibodies are drug-dependent (i.e., will only react in vitro in the presence of the drug). The most common… CONTINUE READING


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