Immune evasion in ebolavirus infections.

  title={Immune evasion in ebolavirus infections.},
  author={Jonathan Audet and Gary P Kobinger},
  journal={Viral immunology},
  volume={28 1},
Ebola virus (EBOV) infects humans as well as several animal species. It can lead to a highly lethal disease, with mortality rates approaching 90% in primates. Recent advances have deepened our understanding of how this virus is able to prevent the development of protective immune responses. The EBOV genome encodes eight proteins, four of which were shown to interact with the host in ways that counteract the immune response. The viral protein 35 (VP35) is capable of capping dsRNA and interacts… CONTINUE READING


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