Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.

@article{Liang2008ImmuneEI,
  title={Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.},
  author={Chengyu Liang and Jongsoo Lee and Jae U Jung},
  journal={Seminars in cancer biology},
  year={2008},
  volume={18 6},
  pages={
          423-36
        }
}
A hallmark of herpesviruses is a lifelong persistent infection, which often leads to diseases upon immune suppression of infected host. Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), is etiologically linked to the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and Multicentric Castleman's disease (MCD). In order to establish a persistent infection, KSHV dedicates a large portion of its genomic information to sabotage almost… CONTINUE READING

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