Immune effector mechanisms of the nitric oxide pathway in malaria: cytotoxicity versus cytoprotection.

@article{Nahrevanian2006ImmuneEM,
  title={Immune effector mechanisms of the nitric oxide pathway in malaria: cytotoxicity versus cytoprotection.},
  author={Hossein Nahrevanian},
  journal={The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases},
  year={2006},
  volume={10 4},
  pages={283-92}
}
Nitric oxide (NO) is thought to be an important mediator and critical signaling molecule for malaria immunopathology; it is also a target for therapy and for vaccine. Inducible nitric oxide synthase (iNOS) is synthesized by a number of cell types under inflammatory conditions. The most relevant known triggers for its expression are endotoxins and cytokines. To date, there have been conflicting reports concerning the clinical significance of NO in malaria. Some researchers have proposed that NO… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 72 references

Immunology of malaria

M. Hommel
World Health Organisation. ed. WHO, Health co-operation papers, Quaderni di cooperazion sanitaria, • 1996
View 9 Excerpts
Highly Influenced

Malaria, principles and practice of malariology

W. H. Wernsdorfer, S. J. McGregor
UK Churchill Livingstone Ltd, • 1988
View 4 Excerpts
Highly Influenced

The development of murine cerebral malaria does not require nitric oxide production

W Rudin
Parasite Immunology • 2002

Nitric oxide autoregulation and its significance

B. StefanoG., I. MagazineH.
Modern Aspects Immunobiol • 2001

Similar Papers

Loading similar papers…