Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice

@inproceedings{Deguise2017ImmuneDM,
  title={Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice},
  author={Marc-Olivier Deguise and Yves de Repentigny and Emily R. McFall and Nicole Auclair and Subash Sad and Rashmi Kothary},
  booktitle={Human molecular genetics},
  year={2017}
}
Spinal muscular atrophy (SMA) has long been solely considered a neurodegenerative disorder. However, recent work has highlighted defects in many other cell types that could contribute to disease aetiology. Interestingly, the immune system has never been extensively studied in SMA. Defects in lymphoid organs could exacerbate disease progression by… CONTINUE READING