Immune dysfunction in uremia.

  title={Immune dysfunction in uremia.},
  author={Gerald Cohen and Marianne Haag-Weber and Walter Hermann H{\"o}rl},
  journal={Kidney international. Supplement},
Among uremic patients on hemodialysis and continuous ambulatory peritoneal dialysis treatment infectious complications leading to a high incidence of morbidity and mortality are a well documented problem. Polymorphonuclear leukocytes (PMNLs) are the main cells of the unspecific defence system during bacterial infections. There is a number of partly interdependent factors responsible for the diminished PMNL functions (chemotaxis, phagocytosis, intracellular killing by proteolytic enzymes and… CONTINUE READING