Immune defects in patients with chronic lymphocytic leukemia

@article{Ravandi2005ImmuneDI,
  title={Immune defects in patients with chronic lymphocytic leukemia},
  author={Farhad Ravandi and Susan H. O’Brien},
  journal={Cancer Immunology, Immunotherapy},
  year={2005},
  volume={55},
  pages={197-209}
}
Over the past decade, the introduction of nucleoside analogs and monoclonal antibodies into the treatment of patients with chronic lymphocytic leukemia (CLL) has resulted in higher rates and longer duration of response. This is a significant step towards achieving the ultimate goal of disease-eradication and improved survival. A continuing problem, however, is the susceptibility of these patients to infections. Profound dysregulation of the host immune system in patients with CLL and its impact… CONTINUE READING