Immune competence and switched memory B cells in common variable immunodeficiency.

@article{Ko2005ImmuneCA,
  title={Immune competence and switched memory B cells in common variable immunodeficiency.},
  author={Jimmy Ko and Lin Radigan and Charlotte Cunningham-Rundles},
  journal={Clinical immunology},
  year={2005},
  volume={116 1},
  pages={37-41}
}
Common variable immunodeficiency (CVID) is presumed to be a heterogenous group of disorders with potentially separate etiologies. Memory B cell subsets, characterized by CD27 expression, have been suggested as a means to subclassify CVID patients. 53 patients were subdivided based on percentages of switched memory B cells (CD27+IgM-IgD-): 33 were placed in Group I (<0.4% CD27+IgM-IgD- cells/peripheral lymphocytes) and 20 in Group II (>0.4%). The median serum IgG for subjects in Group I was… CONTINUE READING