Immune checkpoint inhibitor-induced colitis: A comprehensive review

@article{Som2019ImmuneCI,
  title={Immune checkpoint inhibitor-induced colitis: A comprehensive review},
  author={Aniruddh Som and R. Mandaliya and D. Alsaadi and Maham Farshidpour and A. Charabaty and N. Malhotra and Mark C. Mattar},
  journal={World Journal of Clinical Cases},
  year={2019},
  volume={7},
  pages={405 - 418}
}
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target down-regulators of the anti-cancer immune response: Cytotoxic T-lymphocyte antigen-4, programmed cell death protein-1, and its ligand programmed death-ligand 1. ICIs have revolutionized the treatment of a variety of malignancies. However, many immune-related adverse events have also been described which mainly occurs as the immune system becomes less suppressed, affecting various organs including the gastrointestinal… Expand
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  • PDF
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  • PDF
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  • Highly Influenced
  • PDF
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  • PDF
"Immune checkpoint inhibitor-related luminal GI adverse events".
  • 4
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 89 REFERENCES
Immune Checkpoint Inhibitor-Induced Colitis: Diagnosis and Management
  • 39
Managing immune checkpoint-blocking antibody side effects.
  • M. Postow
  • Medicine
  • American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
  • 2015
  • 295
Vedolizumab treatment for immune checkpoint inhibitor-induced enterocolitis
  • 118
  • PDF
Management of immune-related adverse events and kinetics of response with ipilimumab.
  • 1,031
...
1
2
3
4
5
...