Immune cell dysfunction and inflammation in end-stage renal disease

@article{Betjes2013ImmuneCD,
  title={Immune cell dysfunction and inflammation in end-stage renal disease},
  author={Michiel Gerardus Henricus Betjes},
  journal={Nature Reviews Nephrology},
  year={2013},
  volume={9},
  pages={255-265}
}
Uraemia causes inflammation and reduces immune system function as evidenced by an increased risk of viral-associated cancers, increased susceptibility to infections and decreased vaccination responses in patients with end-stage renal disease (ESRD). The substantially increased risk of atherosclerosis in these patients is also probably related to uraemia-associated inflammation. Uraemia is associated with a reduction in the number and function of lymphoid cells, whereas numbers of myeloid cells… CONTINUE READING
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