Immune cell BDNF secretion is associated with white matter volume in multiple sclerosis

@article{WeinstockGuttman2007ImmuneCB,
  title={Immune cell BDNF secretion is associated with white matter volume in multiple sclerosis},
  author={Bianca Weinstock-Guttman and Robert Zivadinov and Miriam Tama{\~n}o-Blanco and Nadir Abdelrahman and Murali Ramanathan},
  journal={Journal of Neuroimmunology},
  year={2007},
  volume={188},
  pages={167-174}
}
PURPOSE To investigate the relationship between immune cell secretion of brain-derived neurotrophic factor (BDNF) with clinical and MRI variables in multiple sclerosis (MS) patients. BACKGROUND BDNF exerts beneficial effects on neuronal growth and repair and is secreted by both neurons and immune cells. Consequently, it may mediate the crosstalk between the immune system and CNS in autoimmune diseases such as MS. METHODS Fifty-two relapsing MS patients (41 females, age: 48.8+/-6.6 years… CONTINUE READING

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