Immune activation and depression in women with rheumatoid arthritis.

  title={Immune activation and depression in women with rheumatoid arthritis.},
  author={Alex J. Zautra and David C Yocum and Isidro Villanueva and Bruce Golden Robert H. Smith and Mary C. Davis and Jeanne Attrep and Michael R. Irwin},
  journal={The Journal of rheumatology},
  volume={31 3},
OBJECTIVE We examined markers of immune activation during periods of stress and depressive symptoms in 45 female patients with rheumatoid arthritis (RA) in comparison to 106 controls with no autoimmune disease. METHODS Depressive symptoms were recorded, clinician ratings of disease activity were made, and blood was drawn for RA patients and controls at baseline and during a designated stressful week. RESULTS Counts of T cell subpopulations revealed significant differences between RA and… CONTINUE READING
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