Immune activation and chronic inflammation as the cause of malignancy in oral lichen planus: is there any evidence ?

@article{Mignogna2004ImmuneAA,
  title={Immune activation and chronic inflammation as the cause of malignancy in oral lichen planus: is there any evidence ?},
  author={Michele Davido Mignogna and Stefano Fedele and Lucio Lo Russo and Lorenzo Lo Muzio and Eduardo Bucci},
  journal={Oral oncology},
  year={2004},
  volume={40 2},
  pages={120-30}
}
The association of chronic inflammation with a variety of epithelial malignancies has been recognised for centuries. Well established examples include, among many others, oesophageal adenocarcinoma associated with chronic oesophagitis and bowel cancer associated with chronic inflammatory bowel diseases. By now no data, other than clinical observation, have been available in understanding the pathogenesis of these inflammation-related tumours. However, recent molecular studies on the… CONTINUE READING
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