Immune Therapeutic Potential of Stem Cells from Human Supernumerary Teeth

@article{Makino2013ImmuneTP,
  title={Immune Therapeutic Potential of Stem Cells from Human Supernumerary Teeth},
  author={Yuji Makino and Haruyoshi Yamaza and K Akiyama and L. Ma and Yoshihiro Hoshino and Kyohei Nonaka and Yuka Terada and Toshio Kukita and Susan Shi and Takayoshi Yamaza},
  journal={Journal of Dental Research},
  year={2013},
  volume={92},
  pages={609 - 615}
}
Discoveries of immunomodulatory functions in mesenchymal stem cells (MSCs) have suggested that they might have therapeutic utility in treating immune diseases. Recently, a novel MSC population was identified from dental pulp of human supernumerary teeth, and its multipotency characterized. Herein, we first examined the in vitro and in vivo immunomodulatory functions of human supernumerary tooth-derived stem cells (SNTSCs). SNTSCs suppressed not only the viability of T-cells, but also the… CONTINUE READING

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