Immune System in the Brain: A Modulatory Role on Dendritic Spine Morphophysiology?

@inproceedings{BitzerQuintero2012ImmuneSI,
  title={Immune System in the Brain: A Modulatory Role on Dendritic Spine Morphophysiology?},
  author={Oscar Kurt Bitzer-Quintero and Ignacio Gonz{\'a}lez-Burgos},
  booktitle={Neural plasticity},
  year={2012}
}
The central nervous system is closely linked to the immune system at several levels. The brain parenchyma is separated from the periphery by the blood brain barrier, which under normal conditions prevents the entry of mediators such as activated leukocytes, antibodies, complement factors, and cytokines. The myeloid cell lineage plays a crucial role in the development of immune responses at the central level, and it comprises two main subtypes: (1) resident microglia, distributed throughout the… CONTINUE READING
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