Immune Response to Snake Envenoming and Treatment with Antivenom; Complement Activation, Cytokine Production and Mast Cell Degranulation

@inproceedings{Stone2013ImmuneRT,
  title={Immune Response to Snake Envenoming and Treatment with Antivenom; Complement Activation, Cytokine Production and Mast Cell Degranulation},
  author={Shelley F. Stone and Geoffrey K Isbister and Seyed Shahmy and Fahim Mohamed and Chandana Abeysinghe and Harendra Karunathilake and Ariaranee Ariaratnam and Tamara E. Jacoby-Alner and Claire L. Cotterell and Simon G. A. Brown},
  booktitle={PLoS neglected tropical diseases},
  year={2013}
}
BACKGROUND Snake bite is one of the most neglected public health issues in poor rural communities worldwide. In addition to the clinical effects of envenoming, treatment with antivenom frequently causes serious adverse reactions, including hypersensitivity reactions (including anaphylaxis) and pyrogenic reactions. We aimed to investigate the immune responses to Sri Lankan snake envenoming (predominantly by Russell's viper) and antivenom treatment. METHODOLOGY/PRINCIPAL FINDINGS Plasma… CONTINUE READING
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