Immune Response against ALK in Children with ALK-Positive Anaplastic Large Cell Lymphoma

@inproceedings{Stadler2018ImmuneRA,
  title={Immune Response against ALK in Children with ALK-Positive Anaplastic Large Cell Lymphoma},
  author={Serena Stadler and Vijay Kumar Singh and Fabian Knoerr and Christine Damm-Welk and Wilhelm Woessmann},
  booktitle={Cancers},
  year={2018}
}
Patients with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL) mount a humoral and cellular immune response against ALK. More than 90% of children and adolescents with ALK-positive ALCL have detectable anti-ALK antibodies in serum or plasma, and the antibody titer inversely correlates with the risk of relapse. ALK-specific CD8… CONTINUE READING