Immune-Regulatory Mechanisms in Systemic Autoimmune and Rheumatic Diseases

Abstract

Systemic autoimmune and rheumatic diseases (SAIRDs) are thought to develop due to the failure of autoimmune regulation and tolerance. Current therapies, such as biologics, have improved the clinical results of SAIRDs; however, they are not curative treatments. Recently, new discoveries have been made in immune tolerance and inflammation, such as tolerogenic… (More)
DOI: 10.1155/2012/941346

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