Immune Recognition of Candida albicans β-glucan by Dectin-1

@article{Gow2007ImmuneRO,
  title={Immune Recognition of Candida albicans β-glucan by Dectin-1},
  author={N. A. Gow and M. Netea and C. Munro and G. Ferwerda and S. Bates and H. M. Mora-Montes and L. Walker and Trees Jansen and L. Jacobs and Vicky Tsoni and G. Brown and F. Odds and J. Meer and A. J. Brown and B. Kullberg},
  journal={The Journal of Infectious Diseases},
  year={2007},
  volume={196},
  pages={1565-1571}
}
Beta (1,3)-glucans represent 40% of the cell wall of the yeast Candida albicans. The dectin-1 lectin-like receptor has shown to recognize fungal beta (1,3)-glucans and induce innate immune responses. The importance of beta-glucan-dectin-1 pathways for the recognition of C. albicans by human primary blood cells has not been firmly established. In this study we demonstrate that cytokine production by both human peripheral blood mononuclear cells and murine macrophages is dependent on the… Expand
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