Immune-Enhancing Role of Vitamin C and Zinc and Effect on Clinical Conditions

@article{Wintergerst2006ImmuneEnhancingRO,
  title={Immune-Enhancing Role of Vitamin C and Zinc and Effect on Clinical Conditions},
  author={E. Wintergerst and S. Maggini and D. Hornig},
  journal={Annals of Nutrition and Metabolism},
  year={2006},
  volume={50},
  pages={85 - 94}
}
Vitamin C concentrations in the plasma and leukocytes rapidly decline during infections and stress. Supplementation of vitamin C was found to improve components of the human immune system such as antimicrobial and natural killer cell activities, lymphocyte proliferation, chemotaxis, and delayed-type hypersensitivity. Vitamin C contributes to maintaining the redox integrity of cells and thereby protects them against reactive oxygen species generated during the respiratory burst and in the… Expand
Immune-enhancing role of vitamin C and zinc and effect on clinical conditions
TLDR
These trials document that adequate intakes of vitamin C and zinc are found to ameliorate symptoms and shorten the duration of respiratory tract infections including the common cold, and vitaminC and zinc reduce the incidence and improve the outcome of pneumonia, malaria, and diarrhea infections, especially in children in developing countries. Expand
Vitamin C and Immune Function
TLDR
Prophylactic prevention of infection requires dietary vitamin C intakes that provide at least adequate, if not saturating plasma levels, and treatment of established infections requires significantly higher doses to compensate for the increased inflammatory response and metabolic demand. Expand
Vitamin C and the Immune System
TLDR
The vital involvement of vitamin C in the regulation of the immune system to prevent tissue damage is described and how low levels of vitaminC may weaken the immuneSystem is discussed, which highlights the relevance of this essential nutrient for situations known to challenge the immune System. Expand
Vitamin C and vitamin C plus E improve the immune function in the elderly
TLDR
Vitamin C, in elderly participants, improved the immune functions studied which achieved values close to those of young adults, and could contribute to a healthy longevity. Expand
Nutrition and Immunity in Elderly.
TLDR
Aging is associated with increase in chronic disease as well as infections and associated morbidity, which translate into less effective innate and adaptive immune responses and increased susceptibility to infections. Expand
Contribution of Selected Vitamins and Trace Elements to Immune Function
TLDR
Overall, inadequate intake and status of these vitamins and minerals may lead to suppressed immunity, which predisposes to infections and aggravates malnutrition. Expand
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis
TLDR
The importance of an optimal status of relevant nutrients to effectively reduce inflammation and oxidative stress, thereby strengthening the immune system during the COVID-19 crisis is highlighted. Expand
Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses
TLDR
Overall, inadequate intake and status of these vitamins and trace elements may lead to suppressed immunity, which predisposes to infections and aggravates malnutrition, therefore, supplementation with these selected micronutrients can support the body's natural defence system by enhancing all three levels of immunity. Expand
Vitamins C, D and Zinc: Synergistic Roles in Immune Function and Infections
TLDR
The literature on the immune supportive properties of vitamins C, D and zinc and the impact of their supplementation in reducing the incidence or ameliorating symptoms of upper respiratory tract infections, which are among the most common infections in humans are reviewed. Expand
Contribution of selected vitamins and trace elements to immune function
The immune system requires essential nutrients to function efficiently. Inadequate intake and status of vitamins and trace elements may lead to suppressed immunity, which predisposes to infectionsExpand
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