Immortalization of precursors of endodermal, neuroectodermal and mesodermal lineages, following the introduction of the simian virus (SV40) early region into F9 cells.

Abstract

F9 embryonal carcinoma cells were transfected with a hybrid plasmid containing the early genes of the simian virus SV40 under the control of the adenovirus type 5 E1A promoter [21]. These cells were induced to differentiate in aggregates in the presence of retinoic acid (RA). Unlike the derivatives of F9 that are usually obtained in this manner, the plasmid… (More)

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@article{Kellermann1987ImmortalizationOP, title={Immortalization of precursors of endodermal, neuroectodermal and mesodermal lineages, following the introduction of the simian virus (SV40) early region into F9 cells.}, author={Odile Kellermann and Marie-H{\'e}l{\`e}ne Buc-Caron and J. L. Gaillard}, journal={Differentiation; research in biological diversity}, year={1987}, volume={35 3}, pages={197-205} }