Immortalization of normal human gingival keratinocytes and cytological and cytogenetic characterization of the cells

@article{Kubo2008ImmortalizationON,
  title={Immortalization of normal human gingival keratinocytes and cytological and cytogenetic characterization of the cells},
  author={Chikahiro Kubo and Takeo W. Tsutsui and Yukiko Tamura and Shin-ichi Kumakura and Takeki Tsutsui},
  journal={Odontology},
  year={2008},
  volume={97},
  pages={18-31}
}
Most in vitro studies of oral carcinogenesis in human cells are carried out with oral keratinocytes immortalized by human papillomavirus type 16 DNA. However, because various etiological factors for oral cancer are known, it is important to establish new human keratinocyte cell lines useful for studying the mechanism of oral carcinogenesis. Normal human… CONTINUE READING