Immortalization of fibroblasts from two patients with hereditary retinoblastoma.


Two RB fibroblastic strains from patients with hereditary retinoblastoma (RB), namely, RB80F/250R and RB110F, were transfected with plasmid DNAs encoding SV-40 large T-antigen at passage 31 and 10, respectively, These transfected fibroblasts developed into two immortalized cell lines. RB80F/250R/ori- and RB110F/gpt. RB110F/gpt had a similar doubling time as… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.