Immortalization of Human Adipose-Derived Stem Cells as Useful Tool to Produce Cell-Secreted Paracrine Factors for Future Applications in Cell Therapy and Regenerative Medicine

  • Balducci, Saldarelli, and Alessandri
  • Published 2016
Multipotent mesenchymal stem cells (MSCs) were isolated for the first time by Friedstein from adult bone marrow [1]. During the following years, MSCs were identified and isolated from other tissues such as trabecular bone [2], skeletal muscle [3], skin [4] and umbilical cord [5]. Since from their discovery, MSCs became an attractive field of research for… (More)