Immobilizing doses of halothane, isoflurane or propofol, do not preferentially depress noxious heat-evoked responses of rat lumbar dorsal horn neurons with ascending projections.

@article{Barter2008ImmobilizingDO,
  title={Immobilizing doses of halothane, isoflurane or propofol, do not preferentially depress noxious heat-evoked responses of rat lumbar dorsal horn neurons with ascending projections.},
  author={Linda S Barter and Laurie O Mark and Steven L. Jinks and Earl E. Carstens and Joseph Antognini},
  journal={Anesthesia and analgesia},
  year={2008},
  volume={106 3},
  pages={985-90, table of contents}
}
BACKGROUND The spinal cord is an important site where volatile anesthetics decrease sensation and produce immobility. Beyond this knowledge, our understanding of a site of anesthetic action is limited. Previous evidence suggests that dorsal horn neurons with ascending projections may be more susceptible to depression by general anesthetics than local spinal interneurons. In this study we evaluated the effects of volatile and injectable general anesthetics on lumbar dorsal horn neurons with and… CONTINUE READING
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