Immobilization of a human epidermal growth factor receptor 2 mimotope-derived synthetic peptide on Au and its potential application for detection of herceptin in human serum by quartz crystal microbalance.

Abstract

Therapeutic antibodies are antigenically similar to human antibodies and are difficult to detect in assays of human serum samples without the use of the therapeutic antibody's complementary antigen. Herein for the first time, we established a platform to detect Herceptin in solutions by using a small (<2.2 kDa), inexpensive, highly stable human epidermal… (More)
DOI: 10.1021/ac201430p

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@article{Shang2011ImmobilizationOA, title={Immobilization of a human epidermal growth factor receptor 2 mimotope-derived synthetic peptide on Au and its potential application for detection of herceptin in human serum by quartz crystal microbalance.}, author={Yuqin Shang and Pankaj Singh and Mohammad Muhsin Chisti and Ray L. Mernaugh and Xiangqun Zeng}, journal={Analytical chemistry}, year={2011}, volume={83 23}, pages={8928-36} }