Immobilization of Antibodies on a Photoactive Self-Assembled Monolayer on Gold

@article{Delamarche1996ImmobilizationOA,
  title={Immobilization of Antibodies on a Photoactive Self-Assembled Monolayer on Gold},
  author={E. Delamarche and G. Sundarababu and H. Biebuyck and B. Michel and C. Gerber and H. Sigrist and H. Wolf and H. Ringsdorf and N. Xanthopoulos and H. Mathieu},
  journal={Langmuir},
  year={1996},
  volume={12},
  pages={1997-2006}
}
This paper presents a strategy for immobilizing biomolecules on a photoactivable surface. A self-assembled monolayer is prepared by adsorbing an ω-functionalized dialkyl disulfide on gold. Functional groups of this monolayer are converted in two steps into a benzophenone derivative with an overall yield of 50 ± 10%. Several independent techniques (ellipsometry, X-ray photoelectron spectroscopy, scanning electron microscopy, atomic force microscopy, radiolabel assay, and autoradiography… Expand
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