Immobilisation and evaluation of a vancomycin chiral stationary phase for capillary electrochromatography.

@article{Wikstrm2000ImmobilisationAE,
  title={Immobilisation and evaluation of a vancomycin chiral stationary phase for capillary electrochromatography.},
  author={H{\aa}kan Wikstr{\"o}m and Liselott A Svensson and Arne Torstensson and Paul K. Owens},
  journal={Journal of chromatography. A},
  year={2000},
  volume={869 1-2},
  pages={395-409}
}
The macrocyclic antibiotic, vancomycin, is covalently bonded to LiChrospher diol silica packed columns and evaluated in capillary electrochromatography (CEC) both in the reversed-phase and polar organic mode. Initially, capillaries were packed with 5 microm LiChrospher 100 A diol silica and evaluated in CEC with a reversed-phase biphenyl-pyrene achiral test resulting in resolution and efficiency values of ca. 2.5 and 100000 plates meter(-1), respectively. Repeatability for this test (resolution… CONTINUE READING