Immediate versus deferred initiation of androgen deprivation therapy in prostate cancer patients with PSA-only relapse. An observational follow-up study.

@article{GarcaAlbniz2015ImmediateVD,
  title={Immediate versus deferred initiation of androgen deprivation therapy in prostate cancer patients with PSA-only relapse. An observational follow-up study.},
  author={Xabier Garc{\'i}a-Alb{\'e}niz and June Maylin Chan and Alan Paciorek and Roger W. Logan and Stacey A Kenfield and Matthew R Cooperberg and Peter R. Carroll and Miguel A. Hern{\'a}n},
  journal={European journal of cancer},
  year={2015},
  volume={51 7},
  pages={817-24}
}
BACKGROUND The optimal timing to start androgen deprivation therapy (ADT) in prostate cancer patients with rising prostate-specific antigen (PSA) as the only sign of relapse is unknown. METHODS We identified men with prostate cancer in the Cancer of the Prostate Strategic Urologic Research Endeavour (CaPSURE) study who would have been eligible (⩽ cT3aN0M0, primary radical prostatectomy or radiotherapy, PSA relapse as the only evidence of recurrence) for a randomised trial comparing 'immediate… CONTINUE READING
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