Immediate Wheal Reactivity to Autologous Sweat in Atopic Dermatitis Is Associated with Clinical Severity, Serum Total and Specific IgE and Sweat Tryptase Activity.

@article{Ilves2016ImmediateWR,
  title={Immediate Wheal Reactivity to Autologous Sweat in Atopic Dermatitis Is Associated with Clinical Severity, Serum Total and Specific IgE and Sweat Tryptase Activity.},
  author={Tiina Ilves and Anu Virolainen and Ilkka Tapani Harvima},
  journal={International archives of allergy and immunology},
  year={2016},
  volume={170 2},
  pages={84-91}
}
BACKGROUND Sweating can worsen atopic dermatitis (AD). The purpose of this work was to study the associations between reactivity to autologous sweat and the clinical severity of AD as well as investigate the possible wheal-inducing factors of sweat. METHODS Intracutaneous skin tests with autologous sweat were performed on 50 AD patients and 24 control subjects. In skin biopsies, tryptase and PAR-2 were enzyme and immunohistochemically stained. The associations between skin test reactivity and… CONTINUE READING

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: more common in male patients and in head and neck type

  • P Mayser, A Gross
  • 2014

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