Immature stimulus-secretion coupling in the developing exocrine pancreas and ontogenic changes of protein kinase C.

@article{Shimizu1988ImmatureSC,
  title={Immature stimulus-secretion coupling in the developing exocrine pancreas and ontogenic changes of protein kinase C.},
  author={Katsuhiko Shimizu and Emanuel Lebenthal and Ping Chuan Lee},
  journal={Biochimica et biophysica acta},
  year={1988},
  volume={968 2},
  pages={186-91}
}
Previous observations have shown unresponsiveness of pancreatic acini to cholecystokinin C-terminal octapeptide (CCK-8) and cholinergic agents in newborn rats. In this study, the possibility that a lack of protein kinase C may be one factor limiting the responsiveness of the acini was examined. In the term fetus and in newborns cytosolic protein kinase C… CONTINUE READING