Immature small ribosomal subunits can engage in translation initiation in Saccharomyces cerevisiae.

@article{Soudet2010ImmatureSR,
  title={Immature small ribosomal subunits can engage in translation initiation in Saccharomyces cerevisiae.},
  author={Julien Soudet and J P G{\'e}lugne and Kamila Belhabich-Baumas and Mich{\`e}le Caizergues-Ferrer and Annie Mougin},
  journal={The EMBO journal},
  year={2010},
  volume={29 1},
  pages={80-92}
}
It is generally assumed that, in Saccharomyces cerevisiae, immature 40S ribosomal subunits are not competent for translation initiation. Here, we show by different approaches that, in wild-type conditions, a portion of pre-40S particles (pre-SSU) associate with translating ribosomal complexes. When cytoplasmic 20S pre-rRNA processing is impaired, as in Rio1p- or Nob1p-depleted cells, a large part of pre-SSUs is associated with translating ribosomes complexes. Loading of pre-40S particles onto… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

TAp73 contributes to the oxidative stress response by regulating protein synthesis

Proceedings of the National Academy of Sciences of the United States of America • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Making ribosomes.

Current opinion in cell biology • 2002
View 4 Excerpts
Highly Influenced

Ribosomal RNA synthesis in Saccharomyces cerevisiae.

Journal of molecular biology • 1972
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…