Immature and absolute platelet count changes and thrombocytopenia in malignant glioma.

@article{Preusser2011ImmatureAA,
  title={Immature and absolute platelet count changes and thrombocytopenia in malignant glioma.},
  author={Matthias Preusser and Katarzyna Elandt and Ilse Schwarzinger and Christine Marosi and Harald Heinzl},
  journal={European journal of clinical investigation},
  year={2011},
  volume={41 5},
  pages={539-45}
}
BACKGROUND Temozolomide (TMZ) is commonly used for the therapy of malignant glioma and induces thrombocytopenia in a fraction of patients. Currently, no biomarkers predicting TMZ-induced thrombocytopenia are available. In this study, we investigated whether changes in platelet count (PLT) or the immature platelet fraction (IPF) may serve as predictor of TMZ-induced thrombocytopenia in malignant glioma patients. METHODS  We prospectively included 52 malignant glioma patients receiving TMZ… CONTINUE READING