Immature NK cells, capable of producing IL-22, are present in human uterine mucosa.

@article{Male2010ImmatureNC,
  title={Immature NK cells, capable of producing IL-22, are present in human uterine mucosa.},
  author={Victoria Male and Tiffany Hughes and Susan McClory and Francesco Colucci and Michael A. Caligiuri and Ashley Moffett},
  journal={Journal of immunology},
  year={2010},
  volume={185 7},
  pages={3913-8}
}
NK cells are the dominant population of immune cells in the endometrium in the secretory phase of the menstrual cycle and in the decidua in early pregnancy. The possibility that this is a site of NK cell development is of particular interest because of the cyclical death and regeneration of the NK population during the menstrual cycle. To investigate this, we searched for NK developmental stages 1-4, based on expression of CD34, CD117, and CD94. In this study, we report that a heterogeneous… CONTINUE READING

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