Imipramine Protects against Bone Loss by Inhibition of Osteoblast-Derived Microvesicles

Abstract

The maintenance of bone homeostasis is largely dependent upon cellular communication between osteoclasts and osteoblasts. Microvesicles (MVs) represent a novel mechanism for osteoblasts and osteoclasts communication, as has been demonstrated in our previous study. Sphingomyelinases catalyze the hydrolysis of sphingomyelin, which leads to increased membrane… (More)
DOI: 10.3390/ijms18051013

Topics

Cite this paper

@inproceedings{Deng2017ImipraminePA, title={Imipramine Protects against Bone Loss by Inhibition of Osteoblast-Derived Microvesicles}, author={Lili Deng and Ying Peng and Yuhai Jiang and Yu Wu and Yuedi Ding and Yaping Wang and Dong Xu and Qiang Fu}, booktitle={International journal of molecular sciences}, year={2017} }