Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study.

@article{Labarthe2007ImatinibCW,
  title={Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study.},
  author={Adrienne de Labarthe and Philippe Rousselot and Françoise Huguet-Rigal and Eric C M Delabesse and Francis Witz and S{\'e}bastien Maury and Delphine Rea and J. -M. Cayuela and M Vekemans and Oum{\'e}daly Reman and Agn{\'e}s Buzyn and Arnaud Pigneux and Martine Escoffre and Yves Chalandon and Elizabeth A Macintyre and V{\'e}ronique Lh{\'e}ritier and J Vernant and X. Albuquerque Thomas and Norbert Ifrah and Herv{\'e} Dombret},
  journal={Blood},
  year={2007},
  volume={109 4},
  pages={1408-13}
}
The combination of imatinib with chemotherapy has been recently reported as very promising in patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). During 2004 and 2005, 45 patients with newly diagnosed Ph+ ALL were treated in the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAAPH) 2003 study, in which imatinib was started with HAM (mitoxantrone with intermediate-dose cytarabine) consolidation in good early responders (corticosensitive and… CONTINUE READING

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References

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and lymphoid blast crisis of chronic myeloid leukemia

  • H Dombret, F Witz, S deBotton
  • 2006

Outcome with the hyper-CVAD and imatinib mesylate regimen in Philadelphia (Ph) positive acute lymphocytic leukemia [abstract

  • DA Thomas, S Faderl, J Cortes
  • Abstract
  • 2005

Dramatic improvement in CR rate and CR duration with imatinib in adult and elderly Ph ALL patients: results of the GIMEMA prospective study LAL0201 [abstract

  • M Vignetti, P Fazi, G Meloni
  • Abstract
  • 2004

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