Imatinib and Panax Ginseng: A Potential Interaction Resulting in Liver Toxicity

@article{Bilgi2010ImatinibAP,
  title={Imatinib and Panax Ginseng: A Potential Interaction Resulting in Liver Toxicity},
  author={Naveen Bilgi and Kimberly Bell and Ashwin N. Ananthakrishnan and Ehab Atallah},
  journal={Annals of Pharmacotherapy},
  year={2010},
  volume={44},
  pages={926 - 928}
}
OBJECTIVE: To report a case of imatinib-induced hepatotoxicity after concurrent ginseng ingestion in a patient with chronic myelogenous leukemia (CML). CASE SUMMARY: A 26-year-old man with CML who had taken imatinib 400 mg daily for 7 years with no complications presented with right upper quadrant pain. Laboratory test results included alanine aminotransferase 1069 U/L, aspartate aminotransferase 481 U/L, alkaline phosphatase 124 IU/L, total bilirubin 1.4 mg/dL, albumin 4.0 g/dL, and… 

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