Imaging the spatiotemporal organization of neural activity in the developing spinal cord.

@article{ODonovan2008ImagingTS,
  title={Imaging the spatiotemporal organization of neural activity in the developing spinal cord.},
  author={Michael J. O'Donovan and Agn{\`e}s Bonnot and George Z. Mentis and Yoshi Arai and Nikolai Chub and Neil A Shneider and Peter Wenner},
  journal={Developmental neurobiology},
  year={2008},
  volume={68 6},
  pages={788-803}
}
In this review, we discuss the use of imaging to visualize the spatiotemporal organization of network activity in the developing spinal cord of the chick embryo and the neonatal mouse. We describe several different methods for loading ion- and voltage-sensitive dyes into spinal neurons and consider the advantages and limitations of each one. We review work in the chick embryo, suggesting that motoneurons play a critical role in the initiation of each cycle of spontaneous network activity and… CONTINUE READING