Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators.

@article{Weitz2013ImagingTR,
  title={Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators.},
  author={A. C. Weitz and Matthew R. Behrend and Nan Sook Lee and Ronald L. Klein and Vince A. Chiodo and William W. Hauswirth and Mark S. Humayun and James D. Weiland and Robert H. Chow},
  journal={Journal of neurophysiology},
  year={2013},
  volume={109 7},
  pages={1979-88}
}
Epiretinal implants for the blind are designed to stimulate surviving retinal neurons, thus bypassing the diseased photoreceptor layer. Single-unit or multielectrode recordings from isolated animal retina are commonly used to inform the design of these implants. However, such electrical recordings provide limited information about the spatial patterns of retinal activation. Calcium imaging overcomes this limitation, as imaging enables high spatial resolution mapping of retinal ganglion cell… CONTINUE READING
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