Imaging small human prostate cancer xenografts after pretargeting with bispecific bombesin-antibody complexes and targeting with high specific radioactivity labeled polymer-drug conjugates

@article{Patil2011ImagingSH,
  title={Imaging small human prostate cancer xenografts after pretargeting with bispecific bombesin-antibody complexes and targeting with high specific radioactivity labeled polymer-drug conjugates},
  author={Vishwesh Patil and Keyur S. Gada and Rajiv Panwar and Alexandra D. Varvarigou and Stan Majewski and Andrew G. Weisenberger and Craig Ferris and Yared Tekabe and B A Khaw},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2011},
  volume={39},
  pages={824-839}
}
Pretargeting with bispecific monoclonal antibodies (bsMAb) for tumor imaging was developed to enhance target to background activity ratios. Visualization of tumors was achieved by the delivery of mono- and divalent radiolabeled haptens. To improve the ability to image tumors with bsMAb, we have combined the pretargeting approach with targeting of high… CONTINUE READING