Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.
@article{Jennings2014ImagingPP,
title={Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.},
author={Danna Jennings and Andrew D. Siderowf and Matthew B. Stern and John Seibyl and Shirley Eberly and David Oakes and Kenneth Marek},
journal={Neurology},
year={2014},
volume={83 19},
pages={
1739-46
}
}
OBJECTIVES
The purpose of this study is to evaluate the relative risk of abnormal dopamine transporter (DAT) imaging for subjects with and without hyposmia and the feasibility of acquiring a large, community-based, 2-tiered biomarker assessment strategy to detect prodromal Parkinson disease (PD).
METHODS
In this observational study, individuals without a diagnosis of PD, recruited through 16 movement disorder clinics, underwent tier 1 assessments (olfactory testing, questionnaires). Tier 2… CONTINUE READING