Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.

  title={Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.},
  author={Danna Jennings and Andrew D. Siderowf and Matthew B. Stern and John Seibyl and Shirley Eberly and David Oakes and Kenneth Marek},
  volume={83 19},
OBJECTIVES The purpose of this study is to evaluate the relative risk of abnormal dopamine transporter (DAT) imaging for subjects with and without hyposmia and the feasibility of acquiring a large, community-based, 2-tiered biomarker assessment strategy to detect prodromal Parkinson disease (PD). METHODS In this observational study, individuals without a diagnosis of PD, recruited through 16 movement disorder clinics, underwent tier 1 assessments (olfactory testing, questionnaires). Tier 2… CONTINUE READING
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