Imaging of tumour therapy responses by dynamic CT.

@article{Harvey1999ImagingOT,
  title={Imaging of tumour therapy responses by dynamic CT.},
  author={Chris J. Harvey and Anthony Dooher and Jeffrey A. Morgan and Martin J. K. Blomley and Peter Dawson},
  journal={European journal of radiology},
  year={1999},
  volume={30 3},
  pages={221-6}
}
The objective of this study was to investigate whether functional CT with Patlak analysis could be used to demonstrate acute changes associated with radiotherapy. Patlak analysis yields fractional vascular volume and contrast clearance per unit volume (a measure of permeability). Four tumour types (prostate, bronchus, breast and cervix) were studied pre-radiotherapy and at 1-2 weeks and 6-12 weeks post-therapy. Significant rises in fractional vascular volume and contrast clearance were shown at… CONTINUE READING